Whey Protein

Whey protein is claimed to be useful for various purposes, such as for controlling weight, preventing infections, and treating heart disease. Although there is insufficient evidence supporting these claims, it is thought that whey protein may decrease the risk of food allergies and help people with HIV or AIDS to gain weight. Possible side effects include headaches, fatigue, and thirst.

What Is Whey Protein?

Whey protein is a byproduct of cheese manufacturing. Essentially, it is protein from cow's milk. It is frequently used as a dietary supplement, especially by bodybuilders. It is also claimed to be helpful for numerous other uses, such as for weight control. Whey protein is also used to make many types of baby formula.
 
(Click Benefits of Whey Protein for more information on what the supplement is used for.)
 

How Does It Work?

Whey protein contains a mixture of different compounds, depending on the purity of the whey protein. Some types are minimally processed and filtered, leaving some carbohydrates (including lactose) in with the protein. Other forms are highly filtered and refined, leaving just the protein.
 
There are numerous different proteins in whey protein, including some immunoglobulins (antibodies), which might help prevent infections or have other effects on the immune system. Whey protein also contains a compound that the body uses to make glutathione, an important antioxidant that helps protect cells from damage due to a variety of different stresses. This activity might also provide some benefit for cancer prevention.
 
Some researchers think that whey protein might be beneficial for heart disease, as some forms of this protein might work like a class of blood pressure medications known as angiotensin-converting enzyme inhibitors (ACE inhibitors).
 
Lastly, there is some interest in using whey protein as part of a high-protein, low-carbohydrate weight loss diet.
 

Is Whey Protein Effective?

In general, there is not enough scientific evidence to suggest that whey protein really is effective for most uses. The protein might be useful for decreasing the risk of food allergies (especially milk allergy) in high-risk infants and might help people who have HIV or AIDS to gain weight (see Does Whey Protein Work? for more information).
 

Dosing Information

There is no established standard dosage for whey protein, although general guidelines may be obtained from a few clinical studies that evaluated certain uses of the supplement.
 
(Click Whey Protein Dosage for more information.)
 

Side Effects of Whey Protein

People sometimes assume that dietary supplements are automatically free of side effects. However, this is usually not the case. In studies, there have been reported side effects of whey protein, including (but not limited to):
 
  • Increased stool frequency
  • Headaches
  • Loss of appetite
  • Fatigue
  • Thirst.
     
(Click Whey Protein Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

Drug Interactions

Theoretically, whey protein may interact with a few medications (see Whey Protein Drug Interactions).
 

Safety of Whey Protein

A normal consumption of whey protein (though food) is safe for most people. Medicinal use also appears to be safe in many circumstances. Some people may be more likely to experience problems due to whey protein. Therefore, you should talk with your healthcare provider prior to taking it medicinally if you:
 
Make sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is Whey Protein Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

It is not known what exactly to expect from an overdose of this supplement. If you think you or someone else may have taken too much, it is important to seek immediate medical attention.
 
(Click Whey Protein Overdose for more information.)
 

Storage Methods for Whey Protein

Refer to the label of your individual product for information on how best to store whey protein supplements. Keep all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Other Articles in This eMedTV Presentation