Weight Loss Drugs

Diabetes Drugs
The diabetes medication metformin (Glucophage®) may promote small amounts of weight loss in people with obesity and type 2 diabetes. How this medication promotes weight loss is not clear, although research has shown reduced hunger and food intake in people taking the drug.
(Click Metformin and Weight Loss for more information.)
Exenatide (Byetta®), an injectable medication approved to treat type 2 diabetes, also has been shown to cause weight loss. The drug likely works by slowing down the rate at which the stomach empties food, helping people feel full for a longer time (see Byetta for Weight Loss).
ADHD Medications
A number of ADHD medications may be used off-label for weight loss. These drugs are amphetamines, so they are less often prescribed for weight loss because they have the potential for abuse and dependence.
Some amphetamines that have been shown to cause weight loss include:
While most amphetamines are not approved for weight loss, the following two have been approved for this use:
These drugs promote weight loss primarily by suppressing the appetite.
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