Meridia Drug Interactions

When certain medications are taken with Meridia, drug interactions can occur. Some of these interactions may affect the levels of medications in your blood, possibly increasing your risk of side effects. Other interactions may cause a group of symptoms called serotonin syndrome, which can be very dangerous. Before taking Meridia, be sure to talk to your healthcare provider about possible drug interactions that may apply to you.

An Introduction to Meridia Drug Interactions

In October 2010, Meridia was withdrawn from the market in the United States. Studies have shown that it increases the risk of heart attacks and strokes. This medication will no longer be available in the United States. People should stop taking it and should ask their healthcare providers about more appropriate weight loss options.
Meridia® (sibutramine hydrochloride monohydrate) can potentially interact with a few other medicines. Some of these medicines that may lead to Meridia interactions include:
  • Certain antibiotics or antifungal medications
  • Certain pain medications, including:



  • Cough, cold, or allergy medications
  • Ergot medications, such as:


    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®








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