Meridia and Pregnancy
In general, animal studies involving Meridia and pregnancy did not suggest that Meridia causes problems during pregnancy. However, when very high doses of Meridia were taken, it did cause birth defects and problems in the pregnant animals themselves. Therefore, the FDA has classified Meridia as a pregnancy Category C medication, meaning it may not be safe for use in pregnant women.
An Overview of Meridia and PregnancyMeridia® (sibutramine hydrochloride monohydrate) is a prescription weight-loss aid that may not be safe for pregnant women. Studies have shown potential problems when Meridia was tested in pregnant animals.
In October 2010, Meridia was withdrawn from the market in the United States. Studies have shown that it increases the risk of heart attacks and strokes. This medication will no longer be available in the United States. People should stop taking it and should ask their healthcare providers about more appropriate weight loss options.
Meridia and Pregnancy Category CThe U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans, but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
In general, animal studies did not suggest that Meridia causes problems during pregnancy. However, a few birth defects were seen when extremely high Meridia doses were used during pregnancy (which were high enough doses to also cause problems in the pregnant animals themselves).
However, it is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to pregnant women if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.