Weight Loss Home > Lipo-6

Lipo-6 is a weight loss pill that may work by increasing metabolism and suppressing the appetite. However, it is unclear how (or even if) it works because no studies have been conducted on it. Side effects could include diarrhea, stroke, or heart attack. Prior to taking Lipo-6, talk to your healthcare provider if you have glaucoma, an enlarged prostate, or any heart problems.

What Is Lipo-6?

Lipo-6™ is a non-prescription herbal weight loss supplement. It is advertised as an "accelerated fat-loss formula."
(Click Lipo-6 Uses for more information.)

Who Makes It?

Lipo-6 is made by Nutrex, Inc.

What's in Lipo-6?

Lipo-6 contains several different ingredients, including:
  • Synephrine (a stimulant)
  • Synthetic 99% guggulsterones Z&E (a manufactured version of certain plant sterols)
  • Yohimbine (an herbal product)
  • Caffeine
  • Bioperine® (a certain brand of black pepper extract).

How Does It Work?

It is not known how (or even if) Lipo-6 works for weight loss. Synephrine is a stimulant that is often used in weight loss supplements to replace ephedra, since ephedra was banned due to safety concerns. However, there is no evidence that synephrine is any safer than ephedra. Synephrine is also sometimes known as bitter orange, since it is one of the key active ingredients in bitter orange. Caffeine is also a stimulant. These stimulants may work to increase metabolism or to suppress the appetite.
Another ingredient, yohimbine, is most often used as an aphrodisiac or antidepressant, so it is not clear how, why, or if it would work for weight loss. Nor is it known how (or even if) the other active ingredients work for weight loss.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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