Lipo-6™ is a non-prescription herbal weight loss supplement. It is advertised as an "accelerated fat-loss formula."
Lipo-6 is made by Nutrex, Inc.
Lipo-6 contains several different ingredients, including:
- Synephrine (a stimulant)
- Synthetic 99% guggulsterones Z&E (a manufactured version of certain plant sterols)
- Yohimbine (an herbal product)
- Caffeine
- Bioperine® (a certain brand of black pepper extract).
It is not known how (or even if) Lipo-6 works for weight loss.
Synephrine is a stimulant that is often used in weight loss supplements to replace
ephedra, since ephedra was banned due to safety concerns. However, there is no evidence that synephrine is any safer than ephedra. Synephrine is also sometimes known as
bitter orange, since it is one of the key active ingredients in bitter orange. Caffeine is also a stimulant. These stimulants may work to increase metabolism or to suppress the appetite.
Another ingredient, yohimbine, is most often used as an aphrodisiac or
antidepressant, so it is not clear how, why, or if it would work for weight loss. Nor is it known how (or even if) the other active ingredients work for weight loss.