GABA (short for
gamma-aminobutyric acid) is an important neurotransmitter in the body. It is also available as a
dietary supplement and is supposedly beneficial for various uses, such as improving mood or promoting weight loss.
GABA is the primary inhibitory neurotransmitter in the central nervous system in adults. This means that when GABA binds to receptors, it usually decreases the chance that a nerve will "fire" and send out a signal. Although drugs that act like GABA or increase the levels are useful for a wide variety of medical conditions, such as
epilepsy and
anxiety, there is no strong evidence that taking this supplement will produce similar effects.
Taking GABA may either increase or decrease human growth hormone (HGH) levels and may increase the level of the hormones
insulin and glucagon.
There is little evidence to suggest that taking GABA supplements is effective for any use
(see Does GABA Work? for more information).
As with most dietary supplements, there is no well-established standard dose for GABA
(see GABA Dosage for more information).
Even though it is a "natural" product, GABA can cause side effects, such as an increased heart rate or increased
blood pressure.
(Click GABA Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
There is very little information available in order to rate the safety of GABA. However, some people may be more likely to experience problems with a supplement or medication. Therefore, you should talk with your healthcare provider prior to taking GABA if you:
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Is GABA Safe? for more information, including any available warnings and precautions.)
What If I Take an Overdose?
It is not clear what exactly to expect from an overdose with this supplement. If you think you or someone else may have taken too much GABA, it is important to seek immediate medical attention.
Refer to the label of your individual product for information on how best to store GABA. Keep all medications and supplements out of the reach of children.
