Didrex Warnings and Precautions

Before you begin your weight-loss treatment with Didrex, warnings and precautions for the drug should be reviewed. This includes talking with your healthcare provider if you have certain medical conditions, such as heart problems, diabetes, or a history of drug or alcohol abuse. Didrex warnings and precautions also extend to women who are pregnant or breastfeeding and people with certain allergies.

Didrex: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Didrex® (benzphetamine hydrochloride) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also be sure to tell your healthcare provider about any other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Didrex Warnings and Precautions

Some warnings and precautions to be aware of prior to taking Didrex include the following:
  • Didrex is chemically similar to amphetamines, which are often abused. Taking Didrex for long lengths of time can lead to dependence. Because Didrex is often abused, there are special rules for prescribing and dispensing Didrex.
  • Didrex can increase your heart rate and blood pressure. This can cause problems, especially if you already have high blood pressure or heart problems.
  • Didrex can make glaucoma worse. Check with your healthcare provider before taking Didrex if you have glaucoma.
  • If you have diabetes and take insulin, your healthcare provider may need to adjust your insulin dosage, as Didrex suppresses the appetite.
  • Before you take Didrex, your healthcare provider should make sure your obesity is not caused by a medical problem.
  • Weight loss medications like Didrex that work by suppressing the appetite (known as "anorectics") have been linked to pulmonary hypertension, a rare but often fatal disorder. Such medications have also been linked to valvular heart disease (diseases affecting the heart valves). People who already have a heart murmur, heart valve problems, very high blood pressure, heart disease, or an irregular heart rhythm (arrhythmia) should not take Didrex.
  • Do not combine Didrex with any other weight loss medications or supplements, as doing so may increase the risk of dangerous side effects such as pulmonary hypertension.
  • Didrex may affect your ability to perform tasks that require complete concentration, such as driving, operating machinery, or piloting an airplane, especially during the first few weeks of treatment. It is recommended that you use caution until you know exactly how Didrex affects you.
  • Didrex can interact with a number of different medications (see Didrex Drug Interactions for more information).
  • Didrex is considered a pregnancy Category X medication. This means that it should never be used during pregnancy (see Didrex and Pregnancy).
  • It is not known if Didrex passes through breast milk. Therefore, if you are breastfeeding or plan to start breastfeeding, discuss this with your healthcare provider prior to taking the drug (see Didrex and Breastfeeding).
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