Does Cylaris Work?

Many people wonder if Cylaris works. The Web site claims that this product has been scientifically proven to cause weight loss based on one small study. However, this study has several design flaws -- for instance, the supplement used in the study was not the same formulation of ingredients as in Cylaris. Until a larger, higher-quality study is conducted, it is not known if Cylaris works for weight loss.

Does Cylaris Work for Weight Loss?

Cylaris™ is a weight loss supplement. The advertisements for it claim that there is scientific evidence supporting the safety and effectiveness of the product. However, careful examination of the one clinical study of Cylaris raises some serious questions about the validity of these claims.
The Cylaris Web site claims that this product has been scientifically proven to cause weight loss, based on the results of one study. However, the name of the study (or any sort of reference) is not provided. Most people do not have the ability to find the study, based on the limited information provided, and will assume the study is reliable. It is very important to understand that not all studies are created equal. There are several important design flaws in the Cylaris study.
Probably most importantly, even though the study claims to use Cylaris, it is not the same formulation that is marketed as Cylaris supplements. The ingredients are not the same (the study did not include caffeine, which is an active ingredient of Cylaris), and the amounts of certain other ingredients are also different. Second, this study included only participants from West Africa, and the results cannot be generalized to a typical North American or European population (who is most likely to buy Cylaris).
There were four groups of people who participated in the study. The first was a placebo group (who took a "sugar pill" with no active ingredients), which consisted of people who were all obese and who did not follow an appropriate diet. The other three groups were given a certain formulation of the supplement and consisted of:
  • People who were obese and not put on a diet
  • People who were obese and followed an appropriate diet
  • Overweight people (who weighed less than obese people).
Clearly, it is not fair to compare a group that was on a diet or a group that was just overweight to an obese, non-dieting placebo group. In addition, there are some very important statistical differences between the baseline characteristics of the people in the various groups. For instance, the people in the placebo group had a wide range of starting weights, compared to the other groups.
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