It is possible that you may experience some or none of these side effects explained above. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have side effects from a medicine that you have never tried. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking chromium picolinate. You should also let your healthcare provider know if you develop something that "just does not seem right" during treatment with chromium picolinate. While it may not be a chromium picolinate side effect, your healthcare provider will be able to diagnose and treat the problem.