5-HTP Drug Interactions

To help minimize the risk of developing 5-HTP drug interactions, it is important to know which medications may not be suitable to take with 5-HTP. Some medications that may interact with 5-HTP include antidepressants, St. John's wort, and MAOIs. Some of these drug interactions with 5-HTP may cause a group of dangerous symptoms called serotonin syndrome, which may include symptoms such as confusion, hallucinations, and difficulty walking.

 

5-HTP Drug Interactions: An Introduction

5-HTP (5-hydroxytryptophan) can potentially interact with a number of medicines. Some of the medicines that can lead to 5-HTP interactions include:
 
  • Antidepressants
  • Meperidine (Demerol®)
  • Monoamine oxidase inhibitors (MAOIs), including:

 

 

 

 

(5-HTP Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;